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Fenethylline (BAN, USAN) is a codrug of amphetamine and theophylline which behaves as a prodrug to both of the aforementioned drugs. It is also spelled phenethylline and fenetylline (INN); other names for it are amphetamin​oethyl​theophylline and amfetyline. The drug was marketed for use as a psychostimulant under the brand names Captagon, Biocapton, and Fitton.

Captagon was first manufactured in 1961 as an alternative to amphetamine and methamphetamine used at the time to treat narcolepsy, fatigue, and the behavioral disorder “minimal brain dysfunction”. Dexamphetamine was already being used by the military to enable soldiers to stay awake for long periods of time and to “enhance courage and bravado”. Captagon was supposed to be a milder version of these medicines. But by the 1980s the U.S. government declared it a controlled substance with no currently accepted medical use. Manufacturing of the drug ceased in the 1980s.

However, illegal manufacture has continued and has recently escalated in the past few years in Europe and the Middle East. Some sources suggest Captagon is one of the more popular recreational drugs among affluent youth in the Middle East.

No doubt the “Captagon” used by the Islamic Forces (ISIS or ISIL) and other extremist groups to enhance their soldier’s abilities today is far removed from the Captagon of the eighties. Instead of just two main ingredients, illegal manufacturing likely combines several highly addictive stimulants with compounding actions into one destructive little pill. This “new age” Captagon, as with any highly addictive substance, is likely to cause irreversible changes in brain circuitry that govern impulse control and judgment, taking away a person’s ability to reason or think rationally.

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